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What is a Cocaine Vaccine?

Similar to a vaccine, a cocaine vaccine has been developed by researchers using a cold virus and a cocaine resembling molecule. It prevents the cocaine from entering the brain, thus eliminating the pleasure feelings caused by cocaine.

We think that sober and clean living is possible with proper treatment and support. Aftercare is imperative when dealing with addicts and alcoholics. Nothing changes if we don't make a change. By learning how to use the tools of recovery we can have successful, joy-filled and drug-free lives.

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Cocaine Vaccine Research

Up until now, the vaccine has been tested on rats and non-human primates. Biologically, non human primates are said to be closer to humans than rats. The success rate of the cocaine vaccine results has urged the researchers to test the vaccine on humans. The tests conducted on rats injected with the virus and cocaine showed less hyperactive behavior than those mice which were given just cocaine.

Researchers attempted to study the effectiveness of the cocaine vaccine in non-human primates by measuring the amount of cocaine attaching itself to the dopamine transporter. If cocaine reaches the brain it prevents the transporter from carrying dopamine out and attaches itself to the dopamine transporter. This keeps the neurotransmitter active in producing a drug high.

An isotope was attached to the dopamine transporter to measure the amount of tracer attaching to the dopamine receptor in presence or absence of cocaine. The activity of the tracer was seen using a Positron Emission Tomography (PET). There was no change in tracer activity in vaccinated and non- vaccinated primates when cocaine was not given. There was a significant drop in activity of tracer when cocaine was given, in non-vaccinated animals.

This means that in the absence of vaccine, cocaine attaches itself to the dopamine receptor by replacing the tracer. The cocaine occupancy of the dopamine receptor in vaccinated primates was reduced to 20% by use of the vaccine. Previous researches have shown that to produce high cocaine should occupy 47% of the dopamine transporter.

The vaccine was further reported to have lasted 13 weeks in rats and 7 weeks in non-human primates. Researches do not know the amount of vaccine shots that would be required for humans to make it effective. With preliminary results being so satisfying, conducting human trials in near future for the cocaine vaccine gives hope to the cocaine addicts in Parma who want to desperately stop using.

Cocaine Vaccine: Methods to Treat Cocaine Addiction in Parma

Thousands of people in Parma suffer from cocaine addiction, and this has serious consequences as far as healthcare expenses and fatalities are concerned. There are several treatments for cocaine addiction in Parma. As far as medications are concerned, methadone works well with heroin addiction, but unfortunately, there is no such alternative for cocaine addiction.

That is why recently scientists have been working on developing a cocaine vaccine. Like methadone, a cocaine vaccine may be able to prevent the pleasurable sensations associated with the addictive.

What Causes Meth Addiction?

Meth intake causes your brain to be flooded with dopamine. It causes the release of extra dopamine and hinders the cleanup of dopamine in the synaptic clefts between neurons. The resultant high is what makes meth so addictive. To attain this same high, addicts go for higher doses, but this results in the depletion of dopamine and other neurotransmitters in the brain. In addition, meth addiction also causes a variety of physical and psychological problems.